10th March 2021
Join Professor Francisco Quintana from Harvard’s Brigham and Women’s Hospital and his colleagues in a discussion about how a team of researchers from multiple countries are working together to create breakthroughs to improve the lives of people with progressive MS. Professor Quintana leads one of three first-of-their-kind International Collaborative Research Networks funded by the International Progressive MS Alliance aimed at developing new, effective treatments for progressive MS.
The team of researchers from the United States, Canada, Israel and the pharmaceutical company, Sanofi Genzyme are focusing on the innate immune system. While the innate immune system normally functions to protect the body from infection, Dr. Quintana and others have found that some innate immune cells in the nervous system promote disease activity in MS. The team has identified several compounds that have the potential to slow or stop MS from progressing.
In addition to this work, the team recently discovered a subset of brain cells that fights MS inflammation with instructions from gut bacteria. These findings could enable new therapeutic approaches to combat MS such as customized probiotics that could turn-on this anti-inflammatory activity.