Alexis and Gemma: together against MS
Alexis and Gemma have been together for 25 years and have a 12-year old son. Alexis has primary progressive MS. In this video, Gemma says she has never seen MS get the better of Alexis. When the Alliance was looking for people with first hand experience of living with progressive MS to join the Scientific Steering Committee she knew Alexis was the perfect person.
Sergio Baranzini: researching the role of gut bacteria in MS
Sergio Baranzini is a professor in the Department of Neurology at the University of California, San Francisco. His research is focusing on the role of gut bacteria in MS, as he explains in this video.
Jonathon Strum: progressive MS takes no prisoners
Jonathan lives in California and cares for his wife, who has secondary progressive MS. Her MS progressed very rapidly after diagnosis and he gave up work for 11 years to care for her. In this film, he explains how MS not only impacts the person with MS, but also the people around them who have to be as supportive as they can be.
Dr Don Mahad: breaking down the barriers
Dr Don Mahad is a Senior Clinical Lecturer, based in Edinburgh, who studies the role of mitochondria in the pathophysiology of neurodegeneration. In this short film he talks about how the International Progressive MS Alliance is helping experts from across the field to work together with the sole aim of developing therapies for people with progressive MS.
Alexis Donnelly: the Alliance is a conductor with an enthusiastic orchestra
Alexis Donnely is from Dublin, Ireland. He has had primary progressive MS for about 25 years and is quadriplegic. In this video he descibes how MS impacts his life and how he felt when he discovered the Alliance, which he describes as "a conductor with an enthusiastic orchestra of the world's best clinical brains."
Nancy Chiaravalloti: addressing cognition in progressive MS
Cognitive problems can impact all aspects of a person's life. We rely on our memory and our processing of information all day, every day. Nancy Chiaravalloti is Director of Neuroscience Research at the Kesler Foundation in New Jersey, USA. Through her work, she is addressing cognitive challenges in MS by developing new treatments that will improve how people with progressive MS function in daily life.
Caroline Sincock: the Alliance from the perspective of a person with MS
Caroline Sincock lives in Glasgow and has secondary progressive MS. She is a member of the International Progressive MS Alliance Scientific Steering Committee, guiding the scientific direction and research activities of the Alliance.
Anthony Feinstein: cognitive rehabilitation in progressive MS
Anthony Feinstein is professor of psychiatry at the University of Toronto. He is also a researcher and is currently focusing on cognitive rehabilitation in people with progressive MS. Up to 70% of people with secondary progressive MS and up to 50% of people with primary progressive MS have cognitive difficulties so this is a big issue to tackle in symptom management.
Anders Svenningsson: shifting the focus of research
Anders Svenningsson is Head of the Neuroimmunology Unit at Umeå University in Sweden. In this video he talks about shifting the focus of research from relapsing-remitting MS to progressive MS, and the importance of patient focused and patient centred design in research.
Dr Steven Petratos: the impact of the Alliance
Dr Petratos' research is focused on identifying progressive MS triggers and understanding what governs long-term disability in people with progressive MS. In this video he talks about the many benefits of initiatives, like the International Progressive MS Alliance, that bring MS societies together to help researchers, industry partners and commercial partners to fast track novel treatments.
Dr Raymond Sobel: investigating links between sugar beets and MS
Dr Raymond Sobel is a neuropathologist at the VA Palo Alto Hospital in Calfornia, USA. His research focuses on the effects of a compound found in sugar beets used in meat and dairy products. Their geographical use resembles that of MS incidence. If susceptibility to MS is due at least in part to exposure to a dietary component, this will suggest ways to prevent and perhaps treat MS.
Dr Marco Salvetti: repurposing registered drugs
Dr Salvetti is a neurologist from the University of Rome Sapienza in Italy. Here he discusses his work and the benefits of repurposing registered drugs for use in people with MS.